Abstract:

The aim is to investigate the relationship between the most broad diameter of primary injury (LEGC), the maximum standardized injury (SUVmax), the average standardized injury (SUVmean), the metabolic tumor volume (MTV) and the total injury glycolysis (TLG) values with the clinical stage. Method: A total of 130 patients with histopathological diagnosis of lung cancer were taken to study in the Department of Nuclear Medicine from 01.01.2012 to 31.12.2014 for the purpose of diagnosing and evolving lung cancer and PET/BT. The LEGÇ, SUVmax, SUVmean, MTV and TLG values obtained from patients' PET/BT images and histopathological subtypes, other clinical and radiological information were recorded. Patients diagnosed with noncellular lung cancer (CADR) were evolved according to the TNM (Tumor lymph nodus, distant metastasis) evolution system using clinical information, PET/BT and other radiological examination results if there is. Those who have been diagnosed with small-cell cancer (KHAK) were classified as limited or common stages. Results: 118 of the men and 12 women involved in the study found a total of 130 patients, with an average age of 63.46 ± 9.96 (December 40-87 years old). Six hundred patients (81.5 percent) had a histopathological diagnosis of ADHD, while 24 patients (18.5 percent) had a ADHD diagnosis. 62 of the KHDAK patients were composed of flat cell cancer, 39 of the adenocarcinoma, and 5 of the other (3 carcinohydroma, 1 large cell and 1 sarcomatoid tumor) diagnoses. The average values of the LEGÇ, SUVmean, SUVmax, the median values of the MTV and TLG, obtained from the PET/BT images, were observed that there was no significant difference between the KHDAK and KHAK patient groups. It was also found that these parameters have no relationship with the stage in KHAK. In KHDAK, the parameters of LEGÇ, SUVmax, SUVmean, MTV and TLG were observed that they were related to the clinical stage. Results: In small-cellular non-pulmonary cancer, primary tumor has been found that higher SUVmax, SUVmean, TV and TLG values predict the advanced clinical stage. This relationship between the metabolic parameters and the clinical stage suggests that PET/BT in KHDAK may be valuable in terms of providing prognostic information.