Abstract:

Acinic cell carcinoma (ACC) is a rarely seen, slowly growing, low-grade malignant neoplasia of the salivary gland. ACC is most frequently detected in the parotid gland, rarely it is localized in a minor salivary gland. Rarely psammoma bodies are seen in neoplasic, and nonneoplasic lesions of the salivary gland. Herein a case with psammoma body-rich ACC is presented together with its differential diagnosis. A 59-year-old male patient consulted our hospital with complaint of stuffy nose persisting for a year. His radiological examination revealed the presence of a mass lesion in the maxillary sinus which expanded neighbouring bony structures. Macroscopically a tumoral mass with a diameter of 6 cm was observed in maxillectomy specimen in sections prepared from the tumor, acini-like structures containing microcalcifications were observed. Tumor cells had basophilic granular cytoplasm, and round or oval shaped nuclei. Tumor cells stained with PAS and dPAS demonstrated cytoplasmic granules. The case was reported as “psammoma body-rich ACC”.

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