Abstract:

Purpose: In this study, the biodegradability for diagnosis was studied by determining the cut-off value of biochemical parameters in female dogs with breast tumor. Tools and Methods: Female dogs brought to our clinic for routine ovariohisterectomy (control group, n = 14) and with breast tumor (CMT group, n = 14) were included in the study. The levels of albumin (ALB), alkaline phosphate (ALP), alanin aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamiltransferase (GGT), total protein (TP), direct bilirubin (DB), total bilirubin (TB), creatine, creatine kinaz-N-acetyl-systeine (CK-NAK), urine, phosphorus (P), magnesium (Mg) and calcium (Ca) were measured by an automatic biochemical analyzer. The findings: ALP (p: 0,048), ALT (p < 0,000), AST (p: 0,043), GGT (p: 0,013), TP (p: 0,010), DB (p: 0,043), TB (p: 0,018), creatine (p < 0,000), P (p < 0,000) and CK-NAC (p < 0,000) levels were more significant than the control group in the CMT group. Although the Mg (p < 0,000) level is higher in the control group, there is no statistical difference between the groups for ALB, urine and Ca levels (p > 0.05). ALP, ALT, AST, GGT, TP and creatin levels were found to be used to diagnose breast tumors with field values below the curve of 0.656, 0.831, 0.610, 0.792, 0.942 and 0.974 respectively. Recommendation: ALP, ALT, AST, GGT, TP and creatin have been found to be helpful diagnostic tools for dog breast tumors.

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