Abstract:

Aim: Simultaneous malignant neoplasms of the ovary and endometrium are noted in about 8% of patients with carcinoma of the uterus, and twice that rate is noted in patients with ovarian carcinoma. When the occurrence is simultaneous, the question arises whether these are simultaneous multiple malignant neoplasms or one is metastatic from the other. The clinical implication and prognosis of these two categories are quite different. This retrospective study was undertaken to review our experience with these fascinating tumors. Material and Method: The clinical records and the pathologic findings of 26 patients with synchronous dual primary ovarian and endometrial carcinomas were reviewed. The median age was 54 years. Findings: The most common presenting symptom was abnormal vaginal bleeding. Most of the patients had early-stage and low- grade disease. 12% of patients had dissimilar histology. Conclusion: Patients with concordant endometrioid tumors of the endometrium and ovary had a 69.1 % 5-year survival rate. The results reveals that the prognosis of primary carcinoma of the uterine corpus and ovary is better than metastatic ones.

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