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Amaç: Üriner sistem infeksiyonları (ÜSİ), hastanede yatan hastalarda en sık görülen infeksiyonlardır. ÜSİ’larından sorumlu etkenler genellikle bakteriler olmakla birlikte, %10’unda fungal etkenler saptanmakta, bunlar arasında da Candida türleri ilk sırada yer almaktadır. Bu çalışmada hastanede yatan hastalarda kandidüri için risk faktörlerinin belirlenmesi amaçlanmıştır. Hastalar ve Yöntem: Çalışmaya Ağustos 2012 – Ağustos 2013 tarihleri arasında Afyon Kocatepe Üniversitesi Tıp Fakültesi Hastanesinde yatan ve idrar kültürlerinde kandida türleri üreyen 18 yaş üstü hastalar dahil edildi. Her hasta için genel risk faktörleri, üriner sisteme yönelik risk faktörleri, kateter kullanım bilgileri, fizik muayene bulguları, biyokimyasal ve mikrobiyolojik laboratuar bulguları izlem formumuza kaydedildi. İzole edilen candida türleri Phoenix yeast ID otomatize sistem ile tiplendirildi. Integral system yeast plus kiti ile antifungal duyarlılık testleri gerçekleştirildi. Bulgular: Çalışmaya 45’i kandidüri saptanan çalışma grubu, 45’i bakteriüri saptanan kontrol grubu olmak üzere 90 hasta alındı. Araştırılan risk faktörlerinden DM (p=0.057), üriner kateter kullanımı (p=0.015), son 30 gün içerisinde invaziv girişim öyküsü (p=0.024) , hastanede yatış süresi (p=0.017), antibiyotik kullanımı (p=0.001), yoğun bakım ünitesinde yatış öyküsü (p=0.058) çalışma grubunda, kontrol grubuna göre anlamlı derecede sık tespit edildi. En sık izole edilen Candida türü C.albicans'tır. Sonuç: Antibiyotiklerin kontrollü kullanımının, üriner katater girişiminin uygun endikasyonlarda yapılmasının, diyabetik hastalarda kan şekeri regülasyonun sağlanmasının ve gerek hastane gerekse yoğun bakım ünitelerinde yatış sürelerinin kısaltılmasının kandidüri sıklığının azaltılmasında etkili olacağı düşünülmüştür.
Purpose: Urinary system infections (URIs) are the most common infections in hospitalized patients. The factors responsible for the bacteria are usually bacteria, but 10 percent of the fungal factors are identified, among which the Candida species are in the first place. This study is aimed at determining risk factors for candidiasis in patients in the hospital. Patients and Method: The study included patients over the age of 18 who lived in the Hospital of the Afyon Kocatepe University School of Medicine between August 2012 and August 2013. General risk factors for each patient, risk factors for the urine system, catheter use information, physical examination findings, biochemical and microbiological laboratory findings were recorded in our monitoring form. The isolated candida species were typed with the Phoenix yeast ID automated system. Integral system yeast plus kit has been performed with antifungal sensitivity tests. Results: The study included 45 candidates and 90 patients, including 45 bacterium-detected control groups. From the risk factors studied, DM (p=0.057), urine katheter use (p=0.015), invasive initiative history (p=0.024) in the last 30 days, hospital stay time (p=0.017), antibiotic use (p=0.001), intensive care unit stay history (p=0. 058) in the work group, the control group was significantly frequently identified. The most commonly isolated Candida type is C.albicans. Conclusion: The controlled use of antibiotics, the initiative of urine catathers in the appropriate indications, the provision of blood sugar regulation in diabetic patients and the shortening of hospitalization periods in hospitalization and intensive care units are considered to be effective in the reduction of the candidate frequency.
Aim: Urinary tract infections (UTI) are the most common infections in hospitalized patients. Although the bacteries are the most common agents of UTI, fungal agents are isolated from %10 of all cases and Candida species are most common in these cases. This study is aimed to determine the risk factors of candiduria in hospitalized patients. Patients and Method: The study included above-18-year-old patients with positive urine cultures for Candida spp who were hospitalized in Afyon Kocatepe University Medical Faculty Hospital between August 2012 and August 2013. We recorded the general risk factors, physical examination findings, biochemical and microbiological laboratory results for each patient. Candida species which are isolat-ed from the patient identified with Phoenix yeast ID automatize system and antifungal sensitivity tested with integral system yeast plus kit. Results: The study included 90 patients; the study group 45 patients who had candiduria, and control group 45 patient who had bacteriuria. Among investigated risk factors, DM (p=0.057), urinary catheter usage (p=0.015), invasive procedure performed in last 30 days (p=0.024), long term hospitalization (p=0.017), antibiotic usage (p=0.001), history of intensive care unite (ICU) admition (p=0.058) were found more frequent in study group then the control group. The most frequent isolated Candida species was C.albicans. Conclusion: Controlled use of antibiotics, performing urinary catheterization with ap propriate indications, regulation of blood sugar in diabetic patients and the shortest appropriate period of hospitalization are thought to be effective in reducing frequency of candidiuria.
Field : Sağlık Bilimleri
Journal Type : Uluslararası
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