Özet:

Objective: The aim was to investigate the relationship between blood gas and complete blood count parameters and mortality in patients with COVID-19 during and after in the intensive care unit (ICU). Material and Methods: Patients were divided as group nonsurvivor and group survivor. Hematological parameters were registered on the day 1, 3, 5. Results: A total of 142 patients were analyzed retrospectively in the study. Out of them, 46 were women (32%). Seventy-one patients were in group nonsurvivor (50%). The median age of group nonsurvivor patients was 61 years, and the median age of group survivor patients was 60 years. Noninvasive ventilation day and mechanical ventilation day were higher in group nonsurvivor. In group nonsurviver, at the admission to the ICU, in the third day and in the fifth day of ICU, PO2/FiO2 (p<0.001), the lymphocyte count (p<0.001), the monocyte count (p<0.010) and the eosinophil percentages (p<0.025) were lower while the neutrophil-lymphocyte ratio was higher (p<0.001) compared to group survivor. At the admission and in third day of ICU, platelet–lymphocyte ratio were higher in group nonsurvivor than group survivor (p<0.020). At the admission, in the third and the fifth day of ICU, systemic immune-inflammation index were higher in group nonsurvivor than group survivor (p<0.011). The effects of PO2/FiO2, hematocrit, monocyte percentage, eosinophil count on mortality were found to be significant. The decrease in monocyte percentage increased the probability of mortality 1.6 times. Conclusion: Changes in blood gas and complete blood count parameters affected the mortality in COVID-19 patients. This study may lead to the development of a more effective treatment strategy by providing a prediction about mortality.