Özet:

OBJECTIVE: Despite the indisputable beneficial effects of regular exercise on health, more data are needed on the underlying molecular pathways that regulate these effects. In this study, it was aimed to investigate the effects of regular combined exercises on serum irisin and insulin levels and lipid profile in sedentary healthy young women. MATERIAL AND METHODS: The sample group of the study consisted of 35 healthy sedentary young women. The mean age of the participants was 21.4±1.94 years, their mean height was 164.3±5.89 cm, and their body weight was 62.2±8.1 kg. The participants were given combined exercises (aerobic + resistance) for 10 weeks, 3 days a week, 75 minutes a day. The variables to be measured in the study (height, body weight, waist and hip circumference, body fat percentage, lipid profile markers, irisin and insulin hormones) were measured before starting the exercise (week 0) and after the exercise application (10 weeks). Data analysis was evaluated with a dependent sample t-test and pearson correlation test. RESULTS: As a result of the evaluation of the data, it was found that 10 weeks of regular combined exercises decreased insulin levels (p=0.003) and increased irisin levels (p=0.012) in sedentary young women. A statistically significant difference was also found in triglyceride values, which is one of the lipid profile markers (p=0.008). CONCLUSIONS: It was determined that the combined exercises performed regularly for 10 weeks have significant effects on irisin and insulin of healthy sedentary young women. It is thought that the application of aerobic and resistance exercises together is an important type of exercise to protect the public health by preventing and treating diseases caused by inactivity.

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