Abstract:

Metal oxide nanoparticles are potential candidate for making future antimicrobials. Increased interest is due to change in fundamental properties at nanoscale. Ni-doped zinc oxide nano-particles were prepared for pharmacological studies. Co-precipitation and solvo-thermal methods were employed which yielded Ni-doped zinc oxide nano-particles and un-doped zinc oxide nano-particles were synthesized via solvo-thermal method. All prepared nano-particles were characterized using X-ray diffraction studies whereas doping was confirmed by Energy Dispersive X-ray analysis. Shape and morphology of these nano-particles was assessed using Scanning Electron Microscopy. The synthesized nano-particles have shown antibacterial activity against both Gram-negative and Gram-positive bacteria designating these nano-particles as future broad spectrum antibacterial. The optical properties were also studied by measuring the energy band gap and were found 1.50 eV for un-doped zinc oxide nano-particles, and it decreases to 1.47 eV for Ni-doped zinc oxide. Ni-doped zinc oxide nanoparticles were proved to be active future pharmaceutical and biomedical agents. 

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