Abstract:

Plasmablastic lymphoma (PBL) is a rare lymphoma first described around twenty years back as a unique entity typically associated with Human Immunodeficiency Viruses (HIV) and affecting the oral cavity. The authors present a case of a 62 years old female who was diagnosed with Plasmablastic Lymphoma (PBL). She had a long standing history of persistent anemia and presented acutely with gastrointestinal symptoms. She was found to have a picture of Tumor Lysis Syndrome and her investigations were initially going with a diagnosis of Plasma Cell Dyscrasia but further investigations determined a diagnosis of PBL. PBL continues to be an uncommon entity and is thus usually missed as part of an initial differential diagnosis. Ongoing studies are limited because of the aggressive nature of the disease making long-term follow-up a challenge.

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