Abstract:

Sebaceoma is a benign neoplasm that originally defined by Troy and Ackerman. It is composed of sebaceous duct-like or cyst-like structures that contain clusters of mature sebaceous cells admixed with basaloid cells. Stroma is eosinophilic and sclerotic. They are most commonly seen in women and decades between 6 and 9, often on the face and scalp. Rippled patern sebaceoma is a recently designated histopathological variant of sebaceoma and a rare subtype. It is characterized by a dermal aggregation of monomorphous, small, basaloid sebaceous germinative cells. The stroma reminds of Verocay bodies. In our case, the patient applied to our hospital with complaints non-healing wound at scalp for 2 years. Material was sent for pathological assessment, and macroscopically has a nodular lesion. Under microscopic assessment, tumor that was localized in the dermis and sharply demarcated from the surrounding tissue was consisting fine granular, hyperchromatic nuclei, basaloid, round or slightly prolonged cells with eosinophilic cytoplasm. Necrosis, atypical mitoses or pleomorphism were not detected. Vacuolated cytoplasmic sebaceous differentiation cells were found scattered. There was formation of cigar-shaped basaloid cells as linear parallel cords in some areas. Cystic epithelium lining the lumina was stained with cytokeratin-19 and cytokeratin-8. Some of vacuolated cells were stained with cytokeratin-19. No staining with cytokeratin-7, S100 and epithelial membrane antigen was observed. Diagnosis of rippled patern sebaceoma was made with these histopathological findings.

Keywords: