Abstract:

Introduction and Objective: Determination of the spread of the tumor after the diagnosis of lung cancer and the retention of the mediastinal lymph nodes; it is important for the development of the tumor stage and operability. In our study, we aimed to determine the effectiveness of the 240 lung cancer outcomes operated in our clinic, the positron emission tomography/computer tomophraphy (PET/BT) findings and the invasive evolution methods, compared with pathological evolution, in indicating the metastasis of the lymphatic nodes. Method and Requirements: In the PET/BT survey of 240 patients taken to study from June 2013 to June 2016, 60 patients were real positive, 45 patients were false positive, 103 patients were real negative, and four patients were false negative. The result of the univariant analysis found that the incidence of the hidden N2 disease in the upper right lob tumors (p=0.01) was statistically significantly high. 160 of the 240 patients received EBUS and 80 received mediastinoscopy. The EBUS pathological studies found real positive in 22 patients, real negative in 120 patients, and false negative in 18 patients. In the comparison of the pathological outcomes of 80 patients in the Mediastinoscopy, a real positive outcomes were found in eight patients, a real negative outcomes in 64 patients and a false negative outcomes in eight patients. The accuracy rates of mediastinoscopin with high specificity rates were found close to EBUS. CONTRIBUTION AND RESULT: As a result of our study, EBUS and mediastinoscopy are in the forefront between evolution methods with high specificity and accuracy. But we believe that mediastinoscopy is still a more golden standard method. In order to determine the patient’s actual stage in terms of both the forecast and the application of the treatment protocol, we believe that the total mediastinal lymphatic nod dissection should be done to the patients with recession.

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