Abstract:

Abstract Merkel cell carcinoma is a high-grade neuroendocrine carcinoma of the skin characterized by cells with a “blastic” appearance, scanty cytoplasm, evenly distributed chromatin. Terminal deoxy-nucleotidyl transferase is a DNA polymerase expressed by thymic T cells lymphoblastic lymphoma/leukemia and some cases of acute myeloid leukemia. Herein, we report a case of Terminal deoxy-nucleotidyl transferase positive small round cell tumor in consistent with Merkel cell carcinoma. Keywords: Merkel cell carcinoma, terminal deoxy-nucleotidyl transferase, leukemia, lymphoma   Özet Merkel hücreli karsinom dağılmış kromatine sahip, dar sitoplazmalı, blastic görünümde morfolojiye sahip derinin yüksek gradeli nöroendokrin tümörüdür. Terminal deoksinükleotidil transferaz lenfoblastik lösemi lenfoma ve bazı akut myeloid lösemilerde timik T hücrelerinden eksprese olan bir DNA polimerazdır. Burada terminal deoksinükleotidil transferaz pozitif merkel hücreli karsinom olgusu sunulmaktadır. Anahtar sözcükler: Merkel hücreli karsinom, terminal deoksinükleotidil transferaz, lösemi, lenfoma

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