Abstract:

Aim: We aimed to evaluate the effect of different parameters on survival in patients with gastric adenocarcinoma who underwent D2 lymph nod disection with more than 15 lymph nodes. Methods: A total of 161 patients with gastric adenocarcinoma, who underwent curative gastrectomy and had more than 15 lymph nodes dissected between January 2001 and January 2015, were retrospectively evaluated. A hundred and forty-six patients were included in the study. Results: The average follow-up period was 24 (12-102) months and the average survival time was 818.80±692.42 (66-3065) days. Gender, age, lymphovascular invasion and perineural invasion, tumor differentiation and histology were not found to have a statistically significant effect on overall survival. Length of hospital stay, tumor location, extent of surgery, chemotherapy, tumor stage (T category), total number of harvested lymph nodes, number of metastatic lymph nodes, lymph nod status (N status), percentage of lymph nod positivity, metastatic lymph nod ratio and stage were found to have a statistically significant effect on overall survival. Conclusion: Having distally located tumor, having chemotherapy, higher total number of harvested lymph nodes and lower N category were better prognostic factor for overall survival in gastric cancer patients having curative resection with more than 15 lymph nodes harvested.