Abstract:

The very rare stromal lesions of prostate are classified in two groups as “prostatic stromal sarcomas” (PSS) and “prostatic stromal proliferation of uncertain malignant potential (PSPUMP)”. 67 year-old male patient admitted with prostatism symptoms and hematuria and transvesical prostatectomy (TVP) was performed with the diagnosis of prostate carcinoma. Histopathological examination of surgical material revealed spindle-cell tumour and with this diagnosis second operation, cystoprostatectomy, was performed. Histopathological examination revealed a tumour composed of fascicle forming, moderately pleomorphic, spindle/oval shaped cells with prominent nucleoli, dense chromatin, 1-3 mitosis in every high power field and necrosis. Immunophenotypically, tumour was vimentin positive. With these findings, the case was diagnosed as prostatic stromal sarcoma. Stromal lesions of prostate are classified as prostatic stromal sarcoma and prostatic stromal proliferation of uncertain malignant potential according to the increased cellularity in stromal cells, nuclear atypia, mitosis, necrosis and stromal overgrowth. A rare case of prostatic stromal sarcoma is presented.

Keywords: