Abstract:

In this study, the effects of exercise on some biochemical parameters as well as nitric oxide (NO), one of the oxidative stress indicators, interleukin-10 (IL-10), one of the main inflammatory cytokines, and caspase-6 activity, one of the apoptosis markers, were determined in 20 Thoroughbred horses. For this purpose, horses were exercised once a day between 11:00 and 13:00for 10 days. Blood samples were taken from the v. jugularis of the animals before and after exercise, and in the serum obtained aspartate aminotransferase (AST), lactate dehydrogenase (LDH), creatine kinase (CK) enzyme activities, glucose, total cholesterol, triglyceride, albumin urea, and creatinine, in plasma NO, IL-10 levels and caspase-6 activities were determined. Exercise did not affect serum AST, LDH, CK, plasma caspase-6 activities, IL-10, and serum albumin levels. However, depending on the exercise; although it is between reference values; a decrease in serum glucose levels, an increase in total cholesterol, triglyceride, urea, creatinine, and plasma NO levels were detected. As a result; it was concluded that the biochemical parameters, oxidative stress, cytokine, and apoptosis markers examined in racehorses may vary depending on the duration, type, and intensity of exercise.

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