Özet:

Aim: Erythrocyte distribution width (RDW) is known to be associated with cardiovascular diseases. Patients with resistant hypertension (RHT) have a higher risk of cardiovascular events. In this study, we aimed to evaluate the relationship between RDW and resistant hy-pertension. Material and Methods: A total of 157 patients, 69 (43%) of them being resistant hyperten-sion, who had 24-hour ambulatory blood pressure measurement (ABPM) were included in this study. RDW and other laboratory parameters were measured after ABPM. Results: The average age in the study population was 57 ± 11, and 77% (121) of the patients were female. Patients were divided into two groups as controlled and RHT. The RDW was significantly higher in the RHT group (14.8±1.4) compared to the CHT group (14.1±1.2); (p=0,02). RDW by multivariable logistic regression analysis (odds ratio [OR]: 1.684, 95% confidence Interval [CI]: 1.250-2.201 p <0.001), diabetes mellitus (OR: 3.459, 95% CI: 1.095-10.930 p = 0.035) and Body Mass Index (BMI) (OR: 1.085, 95% CI: 1.013-1.163 p = 0.02) was found to be an independent predictor of RHT. In the ROC analysis performed of RDW in predicting RHT, the optimal predictive value for RDW was % 14.65 with 62.5% sensitivity and 65.2% specificity. RDW's Area Under Curve (AUC) value was 0.63 (95%CI: 0.551-0.726). Conclusion: RDW, which was found to be associated with high mortality in cardiovascular diseases, was significantly higher in the RHT patient group compared to the CHT patient group, and RDW was found to be an independent predictor of resistant hypertension.

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