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Venöz tromboembolizm, derin ven trombozu ve/veya pulmoner emboli olarak görülen ciddi bir klinik durumdur. Derin ven trombozunun ilk atağını geçiren hastalarda tekrarlama riski artmıştır. Trombofili tromboza yatkınlık olarak tanımlanır ve kalıtsal ya da kazanılmış olabilir. Herediter trombofili idiyopatik pulmoner embolizm ve rekürrensi için önemli bir risk faktörüdür. Heterozigot protrombin G20210A mutasyonu herediter trombofilinin genetik bir formudur ve herediter koagülasyon bozukluklarının ikinci en sık nedenidir. Bu yazıda tekrarlayan pulmoner emboli ve abdominal aortada mural trombüs ile başvuran ve herediter trombofili tespit edilen 76 yaşında bir erkek hastayı sunduk. Bu olgu tekrarlayan pulmoner embolide altta yatan sebebin araştırılması gerektiğini vurgulamak için sunulmuştur.
Venus thromboembolism is a serious clinical condition that manifests as deep venous thrombosis and/or pulmonary embolism. Patients with a first episode of venous thromboembolism are at an increased risk of new episodes. Thrombophilia is defined as a predisposition to thrombosis and may be inherited or acquired. Hereditary thrombophilia is a major risk factor for idiopathic pulmonary embolism and its recurrence. Prothrombin G20210A heterozygosity is a genetic form of thrombophilia named for a specific mutation and is the second common cause of inherited coagulation disorders. We present case of a 76-year-old male patient presenting with recurrent pulmonary embolism and abdominal aortic mural thrombus who was detected hereditary thrombophilia. The cases presented in order to emphasize that etiology should be investigated in recurrent pulmonary embolism.
Venous thromboembolism is a serious clinical condition that manifests as deep venous thrombosis and/or pulmonary embolism. Patients with a first episode of venous thromboembolism are at an increased risk of new episodes. Thrombophilia is defined as a predisposition to thrombosis and may be inherited or acquired. Hereditary thrombophilia is a major risk factor for idiopathic pulmonary embolism and its recurrence. Prothrombin G20210A heterozygosity is a genetic form of thrombophilia named for a specific mutation and is the second common cause of inherited coagulation disorders. We present case of a 76-year-old male patient presenting with recurrent pulmonary embolism and abdominal aortic mural thrombus who was detected hereditary thrombophilia. The casewas presented in order to emphasize that etiology should be investigated in recurrent pulmonary embolism.
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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