Abstract:

Purpose: Preterm early membrane rupture (PEMR) cases were aimed at investigating the forecast of amnion fluid lactate concentration on the act of birth itself; in such cases, information was provided in terms of the standard of maternal and fetal approach. Tools and Methods: This study is designed as a prospective observational study. PEMR phenomena, active water entry between twenty-four to four weeks of pregnancy, were tested in terms of the amnion liquid lactate levels obtained during the sterile speculation examination and the logistic regression analysis used amnion mayii lactate levels and the best cutting values were determined in terms of the entrance of the phenomena into self-born action within 48 hours and 7 days. The average age of the cases was 26.40 ± 6.14 years old. The average pregnancy age during the test was 31.18±2,57 weeks, and the average time to birth (the average±standard error average) was 9.89±1.45 (95% GA: 6.91-12.86) days. The best cutting value in the forecast for the beginning of the birth action within 48 hours and 7 days was 7 mmol/l and 8.1 mmol/l (sensitivity 92.3 %; specificity 36.6 %; positive LR 1.46 %; negative LR 0.21, sensitivity 68.1 %; specificity 57.7 %; positive LR 1.61 %; negative LR 0.55, respectively), but the remaining areas under the curves were not meaningful (AUC=0,56, 95 % GA 0,44-0,67; p=0,380, AUC=0,59, 95 % GA 0,47-0,70; p=0,196 respectively). Result: In this study, the best cuts values were determined in PEMR cases for patients to enter the birth act on their own within 48 hours and 7 days, but for these values there was no statistically meaningful difference between the groups in terms of laktate. In the PEMR cases of active water entry, large-scale, randomized, controlled studies are required to determine the forecast of the amnion fluid lactate levels on entering the birth act by itself.

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