Özet:

INTRODUCTION: We investigated the association between prostate volume and prostate cancer in patients who underwent transrectal prostate biopsy at a single tertiary center. METHODS: In this study, patients who underwent prostate biopsy due to increased serum PSA levels and suspicious findings on digital rectal examination between January 2014 and December 2016 were included. Patient’s age, serum PSA level, findings on digital rectal examination, prostate volume, number of total prostate biopsy core, diagnosis of prostate biopsy (cancer/benign), Gleason score were evaluated. Results: Eight-hundred fourteen patients were included in the study. Mean PSA level was 9.67 ± 6.9 ng/ml and 137 (15.6%) of 814 patients had abnormal digital rectal examination. Mean prostate volume was 44.8 ± 26.5 cm3. Patients divided into 2 groups: 533 (65.4%) of 814 patients had a prostate volume 60 cm3 and lower, 281 (34.6%) of 814 patients had a prostate volume higher than 60 cm3. Patients with a prostate volume 60 cm3 and lower were statistically younger (61.1 ± 9.4 vs. 67.2 ± 8.7, p<0.05) and had a lower serum PSA level (7.9 ± 5.3 vs. 13.5 ± 9.1, p<0.05). Diagnosis of prostate cancer was higher in patients a prostate volume 60 cm3 and lower (40.3% vs. 22.7%, p<0.05). There were no significant differences in the Gleason score between two groups (p=0.792). Discussions and conclusions: We found an association between prostate volume and prostate cancer diagnosis. Patients with a prostate volume higher than 60 cm3 had a decreased rate of prostate cancer diagnosis.

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