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Bu çalışmada 2010-2019 yılları arasında Türkiye’de yapılmış atletik performans ile ilişkili gen-polimorfizm çalışmalarının tek bir kaynak içerisinde toparlanması hedeflenmiştir. Çalışma, 2010 yılından, 25 Kasım 2019 tarihine kadar Türkiye’ de yapılmış çalışmaları kapsamaktadır. Litertür taraması için “Prisma” (Moher ve diğ., 2009) protokolü kullanılmıştır. “Spor, atletik performans, gen, polimorfizm” anahtar kelimeleri kullanılarak “Google Scholar ve Pubmed” veri tabanlarından Türkçe ve İngilizce yayınlanmış araştırmalar taranmış, 19 çalışma araştırmaya dahil edilmiştir. Dahil edilen 19 farklı çalışmada, 10 farklı gen- polimorfizm üzerinde yoğunlaşıldığı tespit edilmiştir. Bu çalışmalarda, ilk sırada ACTN3 R577X gen-polimorfizm (10 farklı çalışma) olurken ikinci sırada ACE (6 farklı çalışma), geri kalan gen polimorfizmlere GNB3 C825T, PPAR-a, PPARGC1A, PPARA rs4253778, Fok1 (rs 2228570), Bsm1 (rs1544410), COMT rs4680 ve SLC6A4 (sadece1’er çalışmada) yer verildiği saptanmıştır. Çalışılan genlerin %80’i (8 adet) (kuvvet ve dayanıklılık) üzerine olurken, iki gen-polimorfizm daha çok bilişssel yatkınlığa odaklıdır. COMT rs4680 dopamin, epinefrin, norepinefrin, SLC6A4 ise seratonin taşıyıcı, anksiyete ve motivasyon odaklı yatkınlığı temsil etmektedir. Duygusal davranışların atletik performansa olan etkisi (korku, heyecan, odaklanma vb.) göz ardı edilemeyeceği için duygusal davranışlarını etkileyen genler ile olan bu iki çalışma da atletik performans içerisine dahil edilmiştir.
This study aimed at recovering gen polymorphism studies related to athletic performance in Turkey between 2010-2019 years within a single source. The study covers the work done in Turkey from 2010 to November 25, 2019. The protocol "Prisma" (Moher and others, 2009) was used for the scan of literature. "Sports, athletic performance, genes, polymorphism" using the keywords "Google Scholar and Pubmed" databases scaned research published in Turkish and English, 19 studies were included in the research. 19 different studies included found that 10 different gen polymorphism was focused on. In these studies, the first place was ACTN3 R577X gen polymorphism (10 different studies), while the second place was ACE (6 different studies), the remaining gen polymorphisms; GNB3 C825T, PPAR-a, PPARGC1A, PPARA rs4253778, Fok1 (rs 2228570), Bsm1 (rs1544410), COMT rs4680 and SLC6A4 (only in the 1st study). While 80% of the genes studied (8 pieces) are on strength and resilience, two gen polymorphisms are more focused on cognitive tendency. COMT rs4680; dopamine, epinephrine, norepinephrine, and SLC6A4 represents seratonin carrier, anxiety and motivation-oriented tendency. The impact of emotional behaviors on the athletic performance (fear, excitement, concentration, etc. These two studies, with genes that affect their emotional behavior because they cannot be ignored, have also been included in the athletic performance.
Between the years 2010-2019 athletic performance-related gene polymorphism studies conducted in Turkey has aimed to summarize in a single source. Research, from 2010 until the date of November 25, 2019 includes studies in Turkey. “Prisma” (Moher et al., 2009) protocol was used for literature scanning. The researches published in Turkish and English from the databases of "Google Scholar and Pubmed" were scanned using the keywords "sports, athletic performance, gene, polymorphism" and 19 studies were included in the research. In 19 different studies included, it was determined that 10 different gene polymorphisms were concentrated. In these studies, ACTN3 R577X gene-polymorphism (10 different studies) was in the first rank, while ACE (6 different studies) ranked second, the remaining gene polymorphisms; It was determined that GNB3 C825T, PPAR-a, PPARGC1A, PPARA rs4253778, Fok1 (rs 2228570), Bsm1 (rs1544410), COMT rs4680 and SLC6A4 (only 1 study) were included. While 80% (8 of the studies) targeted the genes studied for strength and endurance, the two gene polymorphisms focused more on cognitive susceptibility. COMT rs4680; dopamine, epinephrine, norepinephrine, SLC6A4 represent serotonin transporter, anxiety and motivational predisposition. Since the effect of emotional behaviors on athletic performance (fear, excitement, focus etc.) cannot be ignored, these two studies with genes that affect emotional behaviors are included in athletic performance.
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