Özet:

Objectives: To explore the association of perineural invasion with tumor positive cores and tumor volume in TRUS biopsy.Material and Methods: 85 patients, diagnosed with prostate adenocarcinoma via TRUS biopsy were evaluated. Of any observed perineural invasion in any core for each patient was reported as “PNI + ”. Also the amount of tumor in the each core was reported by percentage. Patients were divided into two groups due to their pathology reports which were PNI + or PNI - . Age, PSA, prostate volume, Gleason score, number of biopsy cores, the number of cancer-positive cores, cancer-positive core localizations, percentage of tumor in each core findings were compared statistically between two groups.Results: Of patients 42 49,4% were PNI + and 43 50,6% were PNI - .Median PSA, gleason score and number of tumor positive cores were significantly higher in PNI + group. Also the percentage of tumor in each core was significantly higher in PNI + group p:0.00 , except transition zone P:0.217 . Approximately, tumor percentage in PNI + group was 4 fold of PNI - was. By the association between PNI and tumor positivity in the cores; tumor was being higher in whole cores in PNI + group then the other, except transition zone.Conclusion: It was presented quantitatively in our study that number of tumor positive biSonuç: PNI pozitifliği olan hastaların pozitif kor sayılarını ve biyopsi korlarındaki tümör hacimlerini anlamlı derecede yüksek bulduk ve bunu kantitatif olarak sunduk. Bu bulguların tedavi yöntemini ve yapılacaksa cerrahi yöntemi yönlendirecek ipuçları taşı

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