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Autoimmune hepatitis with eosinophilic infiltration responsive to anti-interleukin-5 receptor treatment: a case report and literature review
2023
Journal:  
Italian Journal of Medicine
Author:  
DOI:  
10.4081/itjm.2023.1619
Abstract:

Inflammatory tissue damage plays a role in the onset, progression, and exacerbation of various chronic autoimmune and metabolic diseases such as autoimmune hepatitis. Here we present a case of autoimmune hepatitis with liver eosinophilic infiltrate in a severe eosinophilic asthma patient who failed conventional immunosuppressive treatment and showed improvement in gastrointestinal symptoms after anti-interleukin-5 receptor treatment. Our case highlights the potential role of eosinophils in initiating or worsening liver inflammation in autoimmune liver disease. The link between eosinophilic inflammation, barrier damage, and chronic autoimmune diseases should be considered in clinical practice.

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2023
Journal:  
Italian Journal of Medicine
Author:  
DOI:  
10.4081/itjm.2023.1619
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Italian Journal of Medicine

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

Metrics
Article : 471
Cite : 10
Details
Italian Journal of Medicine