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COMPARISON OF CONVENTIONAL DISEASE MODIFYING ANTI-RHEUMATIC DRUGS WITH AND WITHOUT INTRA-ARTICULAR PLATELET RICH PLASMA INJECTION IN THE ALTERATION OF DISEASE PROGRESSION OF EARLY RHEUMATOID ARTHRITIS: A RANDOMIZED CONTROLLED TRIAL
2023
Journal:  
International Journal of Advanced Research
Author:  
DOI:  
10.21474/IJAR01/17168
Abstract:

Background and Objectives:Rheumatoid arthritis (RA) is a symmetric inflammatory polyarticular arthritis, where autoimmune response causes chronic inflammation and destruction of joints leading to deformities and affecting the activities of daily living. ACR recommends early diagnosis and aggressive treatment of RA with combination disease modifying anti-rheumatic drugs (DMARDs). Although it attenuates disease progression, long-term remissions have not been adequately achieved. Injection of platelet rich plasma(PRP) decrease joint inflammation by modulating synovial cell proliferation, differentiation and inhibition of catabolic pathways.

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International Journal of Advanced Research

Field :   Sosyal, Beşeri ve İdari Bilimler

Journal Type :   Uluslararası

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Article : 10.413
Cite : 702
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International Journal of Advanced Research