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  Citation Number 6
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Diyabette glisemik kontrolün serum biyokimyasal parametreleri ile ilişkisi
2012
Journal:  
Abant Tıp Dergisi
Author:  
Abstract:

AMAÇ: Bu çalışmanın amacı diyabetes mellitus hastalarını HbA1c düzeylerine göre iyi ve kötü kontrollü diyabet olarak sınıflandırarak glisemik kontrol ile bazı biyokimyasal parametrelerin ilişkisini araştırmaktır.YÖNTEMLER: Çalışmaya 24 iyi kontrollü diyabet HbA1c6,5 hastası ve diyabeti olmayan 29 sağlıklı birey katıldı. HbA1c seviyeleri HPLC yöntemiyle, açlık ve tokluk kan glukozu, kreatinin, trigliserid, total kolesterol ve HDL kolesterol seviyeleri fotometrik, idrar protein ve mikroalbumin düzeyleri türbidimetrik, TSH, sT3, sT4, B12 vitamini ve folik asit seviyeleri elektrokemilüminesans yöntemle ölçüldü.BULGULAR: Kötü kontrollü diyabet hastalarının trigliserid düzeyleri kontrol gurubuna göre anlamlı derecede yüksek bulundu p=0,003 . İdrar mikroalbumin/kreatinin düzeyleri, kötü kontrollü diyabet hastalarında iyi kontrollü diyabet hastalarına göre anlamlı şekilde yüksek bulundu p=0,05 . Diğer parametreler açısından, gruplar arasında anlamlı bir farklılık tespit edilemedi. SONUÇ: Diyabetik hastalarda glisemik kontrol, trigliserid ve mikroalbumin düzeyi ile ilişkili bulunmuştur. Bu veriler, diyabetli hastalarda glisemik kontrolün nefropati ve koroner kalp hastalığı gelişimini etkileyebileceğini düşündürmektedir.

Keywords:

Relationship of glycemic control with serum biochemical parameters
2012
Journal:  
Abant Tıp Dergisi
Author:  
Abstract:

The aim of this study is to investigate the relationship of some biochemical parameters with glycemic control by classifying diabetes mellitus patients as good and poorly controlled diabetes according to HbA1c levels.MOTHERS: The study included 24 well-controlled diabetes HbA1c6,5 patients and 29 healthy individuals without diabetes. HbA1c levels were measured by HPLC method, hunger and emptiness blood glucose, creatine, triglyceride, total cholesterol and HDL cholesterol levels were photometric, urine protein and microalbumin levels were turbidimetric, TSH, sT3, sT4, vitamin B12 and folic acid levels were measured by electrochemiluminess method. The levels of urine microalbumin/creatine were significantly higher in poorly controlled diabetes patients compared to well controlled diabetes patients p=0,05 . In terms of other parameters, a significant difference between the groups was not detected. Results: Diabetic patients have been found related to glycemic control, triglyceride and microalbumin levels. These data suggest that glycemic control in diabetic patients may affect the development of nefropathy and coronary heart disease.

Keywords:

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Abant Tıp Dergisi

Journal Type :   Uluslararası

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Abant Tıp Dergisi