Several factors have been identified in breast carcinoma which affect the biologic behavior, therapy and the prognosis of the tumor. Among these, c-erbB-2 (HER-2/neu) oncogene encodes a transmembrane tyrosine kinase receptor with extensive homology to the Epidermal Growth Factor receptor. In this study, we discuss the prognostic role of c-erbB-2 oncoprotein overexpression in breast carcinoma with and without other parameters on the base of literature.
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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