Abstract Universities have a social responsibility with the formation of new professionals. Keeping stability on its staff is a must, since that guarantees the qualified human resources to achieve educational and research quality. In opposition to this condition, in Latin America and the Caribbean we found an increase in the emigration indicators of professionals to developed countries, many of them from the university centers. Cuba is not an exception, and it has been included inside the currents of brain robbery. The Oriente University, from Santiago de Cuba, showed an increasing staff mobility between the years 2004 and 2013, with a profound incidence of migration to other countries. A motive of attention in this work was the factors associated to that type mobility. For the collection of information that led to the theoretical analysis, we worked with the databases of the university, together with the application of key informant interviews and professors who have emigrated. Besides, we used the data gathered in the questionnaire prepared by the project in which the authors are inserted, answered by professors of the University. This investigation revealed the need to pay attention to factors relating to the migration of professionals in the UO such as: socioeconomic conditions, migratory policies, their professional dissatisfactions and working conditions in their agent-structure relation.
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