Abstract:

SuleymanDemirel University TIP FACULTY JOURNAL: December 2006; 13(4) Tiroid injuries thyroid thin injection biopsy and histopathology comparison of the results of Gülsün Inan, Sevda Hard, Sema Bircan, Nermin Karahan, I. Text Chiriş, Sirin Başpınar, Nilgün Kapucuoğlu Summary Purpose: Tiroid thin injection biopsy (IIAB) results compared with the pathological report results of the events operated, the effectiveness of the IIABs in our faculty in the evaluation of thyroid injuries. Patients and Method: The results of cytology and histopathology of 83 patients with post-IIAB thyroidectomy between 2002-2005 were compared at the SDU Medical Faculty. IIAB results were classified as benign, malignity suspicious, malign and insufficient. The findings: 45 of the sixteen IIAB materials (54.2 percent) are benign, 26 percent (31.3 percent) insufficient, 8 percent (9.6 percent) suspicious of malignity, and 4 percent (4.8 percent) malign. The result of cytology is histologically malignant: 5.i of the events considered beneign, 2.i of the events considered malign and 1.i of the events considered malign. In our study the sensitivity is 37.5%, the specificity is 81.6%, the diagnostic value is 75.4%, the wrong positive value is 18.3%, the wrong negative value is 62.5%, the positive predictive value is 25%, the negative predictive value is 88.8. When the incidental papillary microcarcinoma diagnosed occurrences were excluded, sensitivity was 75%, specificity 81.6, diagnostic value 81.1, negative positive value 18.3, negative negative value 25%, positive predictive value 25%, negative predictive value 97.5%. Result: IIAB is a valuable diagnostic method when papillary microcarsinom diagnosis is excluded in the assessment of thyroid lesions. The comparison of fine needle aspiration biopsy and histopathology results in thyroid lesions Purpose: To determine the utility of fine needle aspiration biopsy (FNAB) in the evaluation of thyroid lesions at our faculty by comparing the results of FNAB and pathology report results of the patients who underwent surgery. Patients and Method: We compared the cytological and histopathological results of 83 patients who underwent thyroidectomies after FNAB at the Suleyman Demirel University School of Medicine between 2002 and 2005. FNAB results were categorized as benign, suspicious for malignancy, malign and insufficient. Results: The diagnosis of FNAB of 83 cases were benign, insufficient, suspicious for malignancy and malign in 45(54.2%), 26(31.3%), 8(9.6%), 4(4.8%) cases respectively. Five of cases which were cytologically diagnosed as benign, 2 of cases which were cytologically diagnosed as suspicious for malignity and 1 of cases which were cytologically diagnosed as malign were found to be malign histologically. Sensitivity, specificity, accuracy, false-positivity, false-negativity, positive predictive value and negative predictive value were 37.5% 81.6%, 75.4%, 18.3%, 62.5%, 25% and 88.8%, respectively. When the incidental papillary microcarcinomas excluded sensitivity, specificity, accuracy, false-positivity, false-negativity, positive predictive value, negative predictive value were changed to 75%, 81.6%, 81.1%, 18.3%, 25%, 25%, 97.5%, respectively. Conclusion: FNAB is a valuable diagnostic method in the evaluation of thyroid lesions when papillary microcarcinomas excluded. Key words: thyroid, FNAB, papillary microcarcinoma, surgical specimen

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