Özet:

This study aimed to research the presence of malignancy in patients with Hashimoto’s thyroiditis, and to examine the reliability of preoperative fine-needle aspiration biopsy (FNAB). Material and Method: This retrospective study included 66 patients who were operated on due to nodular goiter between July 2011 and December 2014. The patients underwent thyroidectomy following a cytologic analysis with FNAB. Hashimoto’s thyroiditis was testified with histopathology in all patients. Results: FNAB outcome were described as malignant in 13 (19.6%), benign in 21 (31.8%), inadequate in 7 (10.6%), and suspicion for malignancy in 25 (37.8%) cases. After thyroidectomy, existence of papillary thyroid carcinoma and follicular variant of papillary thyroid carcinoma were found in 14 (21.2%) and 2 (3.0%) patients, respectively. With regard to malignancy, FNAB displayed a specificity of 39%; sensitivity of 79%; false negative ratio of 13.9%; false positive ratio of 70.1%; positive predictive value of 32.1%; diagnostic accuracy of 51%; and negative predictive value of 86.0%. Conclusion: This coexistence of Hashimoto’s thyroiditis and papillary thyroid carcinoma is fairly mutual. FNAB outcome for such cases are difficult to score, and they are probably to rise the number of false positive cases.

Anahtar Kelimeler: