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Bu çalışmanın amacı 8 haftalık düzenli egzersizin kilolu kadınlarda karaciğer enzimlerine olan etkisinin araştırılmasıdır. Araştırmaya yaş ortalaması 31,3±6,4 yıl, VKI(Vücut kütle indeksi) ortalaması 30,8±1,5 olan 20 gönüllü kadın katılmıştır. Araştırma grubu 10’ar kişilik kontrol ve uygulama grubu olarak iki gruba ayrılmıştır. Kontrol grubu herhangi bir fiziksel aktivite programına katılmazken, uygulama grubu 8 hafta boyunca haftada 4 gün fitness egzersiz programına katılmıştır. Çalışmanın başlangıcında ve 8 hafta (60dk/4 gün/hafta) süren Fitness egzersizlerin sonunda olmak üzere katılımcılardan istirahat halinde iki defa alınan kan örneklerinde AST, ALT ve LDH seviyeleri tespit edilmiştir. Elde edilen verilerin analizi için SPSS paket program kullanılmıştır. Gruplar arasındaki farklılıkları belirlemek için bağımsız örneklerde t testi, grup içi farklılıkları belirlemek için bağımlı örneklerde t testi kullanılmıştır. Uygulama sonunda kontrol grubunun ön test ve son test değerlerinde anlamlı bir farklılığın oluşmadığı (p>0,05) ancak 8 haftalık egzersiz programı sonrası uygulama grubunun AST, ALT ve LDH değerlerinin ön test değerlerine göre anlamlı bir şekilde değiştiği tespit edilmiştir (p<0,05). Bu farklılık gruplar arasında da önemlidir (p<0,05). Bulgularımız kilolu kadınlarda 8 haftalık egzersiz uygulamasının AST, ALT ve LDH seviyelerini değiştirdiğini göstermektedir. Sonuç olarak egzersize yeni başlayan kilolu kadınlarda egzersizin etkisi ile enzim aktivitelerinde bir değişimin olabileceği görülmektedir. Sağlık açısından bu değişimlerin daha olumlu olması için daha uzun süreli egzersizlere ihtiyaç duyulabileceği söylenebilir.
The aim of this study was to investigate the effects of 8 weeks regular exercise on liver enzymes in overweight women. Twenty women with an average age of 31.3 ± 6.4 years and a BMI (Body Mass Index) of 30.8 ± 1.5 participated in the study voluntarily. The participants were divided equally into two groups as control and exercise group. While the control group did not participate in any physical activity program, the exercise group participated in the fitness exercise program 4 days a week for 8 weeks. AST, ALT and LDH levels were determined from blood samples taken twice from the participants during rest, once at the beginning of the study, and once at the end 8-week-long (60min/4day/week) fitness exercise. SPSS software was used for the analysis of the obtained data. The independent samples t test was used to determine the differences between the groups and the paired samples t test was used to determine the differences within the groups. There were no significant differences between pre and post tests in control group (p>0,05), however there were significant differences in AST, ALT and LDH values in exercise group between pre and post tests after 8 week-long exercise program (p<0,05). This difference is also significant between the groups (p <0.05). Our findings show that 8 week-long regular exercise program changes the level of AST, ALT and LDH in overweight females. As a result, it can be seen that there might be a change in enzyme activities with the effect of exercise in overweight women who have recently started to exercise. It can be said that longer-term exercises may be needed to make these changes more positive in terms of health.
The aim of this study was to investigate the effects of 8 weeks regular exercise on liver enzymes in overweight women. Twenty women with a mean age of 31.3 ± 6.4 years and a BMI (Body Mass Index) of 30.8 ± 1.5 participated in the study voluntarily. The participants were divided equally into two groups as control and exercise group. While the control group did not participate in any physical activity program, the exercise group participated in the fitness exercise program 4 days a week for 8 weeks. AST, ALT and LDH levels were determined from blood samples taken twice from the participants during rest, once at the beginning of the study, and once at the end 8-week-long (60min/4day/week) fitness exercise. SPSS software was used for the analysis of the obtained data. The independent samples t test was used to determine the differences between the groups and the paired samples t test was used to determine the differences within the groups. There were no significant differences between pre and post tests in control group (p>0,05), however there were significant differences in AST, ALT and LDH values in exercise group between pre and post tests after 8 week-long exercise program (p<0,05). This difference is also significant between the groups (p <0.05). Our findings show that 8 week-long regular exercise program changes the level of AST, ALT and LDH in overweight females. As a result, it can be seen that there might be a change in enzyme activities with the effect of exercise in overweight women who have recently started to exercise. It can be said that longer-term exercises may be needed to make these changes more positive in terms of health.
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