Özet:

Microwave ablation, which has been used in recent years to treat cancerous cells and tumors, is a type of invasive thermal therapy that uses heat produced by microwaves. In this study, it was aimed to theoretically obtain the extent of tissue damage in order to ensure control in ablation treatment. It was aimed to analyze the effects of tissue properties, frequency, output power, application time parameters and to determine the relationship between them. In the study, electromagnetic field exposure applied to liver, lung and kidney tissues was modeled with the COMSOL Multiphysics program, and the specific absorption rate (SAR), temperature distribution and damage level on the tissues were calculated using the numerical analysis method. Bio-thermal and electromagnetic equations and three-dimensional finite element method (FEM) were used to obtain the temperature gradient. Numerical analysis results are given as temperature distribution, SAR and lesion sizes. It has been found that structural differences of the tissue are an important factor and the ablation zone sizes increase in direct proportion to the achieved temperature as well as frequency, input power and application time. Optimization of parameters is necessary to obtain ablation of the desired shape and size. In the simulation outputs, after 10 minutes of ablation at 2450 MHz frequency and 10 W output power, the approximate coagulation lengths for liver, lung, and kidney were 4.5 cm, 4 cm, and 2.5 cm, respectively; The coagulation diameters were determined as 1.5 cm, 0.8 cm and 0.6 cm, respectively.

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