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Apendiks Müsinöz Neoplazi Hastalarında Klinik Deneyimimiz
2023
Journal:  
Batı Karadeniz Tıp Dergisi
Author:  
Abstract:

Amaç: Apendiks tümörleri gastrointestinal sistemin nadir görülen tümörlerindendir. Apendiksin epitelyal tümörlerinin üçte birini müsinöz neoplazmlar oluşturur. Çalışmada apendiks müsinöz neoplazi hastalarındaki klinik yaklaşımımız ve tedavi sonuçlarımızı literatüre sunmayı amaçladık. Gereç ve Yöntemler: Ocak 2012 - Ocak 2022 yılları arasında apendektomi yapılan 1028 hastanın dosyası geriye dönük olarak incelendi. Histopatolojik tanısı apendiks müsinöz neoplazisi olan hastalar çalışmaya dahil edildi. Hastaların yaş ve cinsiyet verileri, başvuru semptomları, tümör marker değerleri (CEA, CA125, CA19-9), bilgisayarlı tomografi bulguları, ameliyatı yapan cerrahi branş, uygulanan cerrahi yöntemler, frozen verileri, histopatolojik tanıları ve sağ kalım bilgileri kaydedildi. Bulgular: Histopatolojik tanısı müsinöz neoplazm olan 35 (%3.4) hasta vardı. Hastalarımızın 28 (%80)’i kadın, 7 (%20)’si erkekti ve yaş ortalaması 57,5 ± 11.68 yıldı. Karın ağrısı şikayeti ile başvuran 21 (%60), şişkinlik ve ele gelen kitle ile başvuran 9 (%25.7), şikayeti olmayan 5 (%14.2) hasta vardı. Hastaların 7 (%20)’sinde CA125 yüksekliği vardı. Bilgisayarlı tomografide 9 (%25.7) hastada akut apandisit bulgusu mevcuttu. Hastaların 28 (%80)’ine sadece apendektomi, 5 (%14.2)’ine sağ hemikolektomi, 2’sine de apendektomi sonrası sitoredüksiyon + hipertermik intraperitoneal kemoterapi yapılmıştı. Mortalite sayımız 4 (%11.4)’tü. Sonuç: Pelvik kaynaklı kitlesel lezyonlarda anatomik komşuluk nedeniyle apendiks müsinöz neoplazileri akılda tutulmalı, hastalar multidisipliner değerlendirilmeli ve gereğinde ameliyat anında yapılacak frozen incelemelerle tedavi şekillendirilmelidir.

Keywords:

Our Clinical Experience In Patients With Appendix Mucinous Neoplasia
2023
Author:  
Abstract:

Aim: Appendix tumors are a rare tumor of the gastrointestinal system. One-third of epithelial tumors of the appendix are mucinous neoplasms. In this study, we aim to provide literature with our clinical approach and treatment results for appendiks mucinous neoplasia patients. Material and Methods: The files of 1028 patients who underwent appendectomy between January 2012 and January 2022 were examined retrospectively. Patients with a histopathological diagnosis of appendiceal mucinous neoplasia were included in the study. The patients' age and gender data, presenting symptoms, tumor marker values (CEA, CA125, CA19-9), computed tomography findings, surgical branch performing the surgery, applied surgical methods, frozen data, histopathological diagnoses and survival information were recorded. Results: There were 35 (3.4%) patients whose histopathological diagnosis was mucinous neoplasm. Twenty-eight (80%) of our patients were female, 7 (20%) were male, and the mean age was 57.5 ± 11.68 years. There were 21 (60%) patients who presented with abdominal pain, 9 (25.7%) patients with bloating and palpable mass, and 5 (14.2%) patients without complaints. 7 (20%) of the patients had elevated CA125. Computed tomography revealed acute appendicitis in 9 (25.7%) patients. Of the patients, 28 (80%) underwent appendectomy only, 5 (14.2%) right hemicolectomy, and 2 patients underwent cytoreduction + hyperthermic intraperitoneal chemotherapy after appendectomy. Our mortality number was four (11.4%). Conclusion: In mass lesions of pelvic origin, appendiceal mucinous neoplasia should be kept in mind due to anatomical proximity, patients should be evaluated multidisciplinary and treatment should be shaped by frozen examinations to be performed at the time of surgery, if necessary.

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Batı Karadeniz Tıp Dergisi

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

Metrics
Article : 285
Cite : 233
2023 Impact : 0.059
Batı Karadeniz Tıp Dergisi