Abstract:

Objective: We aimed to investigate the relationship between the localization of colorectal carcinomas and the topographic distribution of metastatic liver lesions. Material and Methods: Patients diagnosed with colorectal cancer and metastatic liver lesions constituted the target population of this study. Demographic data, primary tumor localization, and data regarding liver metastases were retrieved and retrospectively reviewed. Patient files, including endoscopy and computerized tomography reports, were the primary data source. In addition, data concerning segmental localization of the metastatic liver lesions based on the Couinaud classification were collected. Results: Ninety-six patients were diagnosed with colorectal cancer with liver metastases during the study period. A total of 251 metastases were detected. The number of metastases was 169 (67.3%) in the right and 80 (31.9%) in the left lobe (p<0.0001). Evaluation regarding Couinaud classification elucidated that the most frequently affected segment was segment VIII (23.1%), while segment 1 (i.e., caudate lobe) was the least commonly affected segment. The liver segments with the highest number of metastatic lesions were VIII, V, VII, VI, III, II, IV, and I, respectively. There was no significant difference in the segmental distribution of metastases in patients with primary tumors in the right and left colon (p>0.05). Conclusion: Liver metastases of colorectal cancer are significantly more common in the right lobe than the left lobe, irrespective of the location of the colorectal tumor. Segment VIII of the right lobe is the main target of the metastases.

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