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Introduction: The intensive care nurse is responsible for caring patients with complex and life-threatening problems. The reasons such as the multiple problems who caring in the intensive care unit, the high care requirements and the lack of care staff can affect the ethical sensitivities, job motivations and hopelessness of the intensive care nurses. Therefore, this study was planned to determine the relationship between moral sensitivity, work motivation and hopelessness in nurses working in intensive care unit. Methods: This descriptive cross-sectional study was conducted between March 2019-May 2019 with nurses working in the intensive care unit of a state hospital. Between 1 March and 5 May, 75 nurses' data were collected. "Socio-Demographic Information Form", "Moral Sensitivity Scale", "Nurses Job Motivation Scale" and "Beck Hopelessness Scale" were used as data collection tools. Ethics committee approval was obtained from the hospital where the research was conducted in. Results: 57.3% of intensive care nurses were male, 77.3% of them were undergraduate and average working year in nursing was found as 8.80± 4.39. The average score of the nurses' job motivation scale was 56.79 ± 7.42, the average of hopelessness scale was 8.92±4.74 and the average score of moral sensitivity scale was 89.35±17.30. A statistically significant relationship was found between the working years of the nurses and their hopelessness (p = 0.032) and work motivations (p = 0.037). According to this, it was determined that as when the working time increased, nurses’ motivation and hopelessness levels were decreasing. In our study, there was a statistically significant relationship between the levels of hopelessness and job motivations of nurses (r = -0.488, p <0.001). As the hopelessness of nurses increases, their job motivation decreases. There was a statistically significant relationship between the moral sensitivities and job motivations of the nurses participated in the study (r = -0.278, p = 0.033). Accordingly, as the moral sensitivities of the nurses' increased, their job motivations decreased. Conclusion: According to our study, it was found that when the hopelessness of nurses increased, their work motivations decreased and when nurses' job motivations decreased as their moral sensitivities increased. No relationship was found between the moral sensitivities and the levels of hopelessness of the intensive care nurses.

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