Özet:

Purpose: To determine the effect of Varyant histology on the pathological and survival results of patients who have been operated with the cause of the urethyl system cancer. Method: Data of 128 patients who had been operated with the cause of urethelial carcinoma in the upper urine system in one center between 2001 and 2019 were reviewed backward. Patients with pure urethelial cancer and those with variable histology were compared with each other in terms of demographic characteristics, pathological results and survival parameters. The average age of the patient was 65±11 years. The female male ratio was 30/98 and the median follow-up period was 26.5 (1-176) months. In 14.8% of the errors varyant histology was detected. Varyant histology was found related to the surgical limit positivity, lymph nod metastasis, the presence of lymphovascular invasion, the high tumor stage and degree (p=0.001, p=0.012, p=0.001, p=0.002, p=0.009, respectively). The three-year cancer specific and general survival rates were identified at 79.6% and 77.3% respectively. A statistically meaningful relationship between variant histology and cancer specific survival and general survival was not established. (p=0.514, p=0.515, respectively) The result: Variant histology in the urethelial carcinoma of the upper urinary system is associated with local advanced disease, while no effect on survival is shown. (SETB-2021-06-175)

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