Objectives: Although the relationship between breast cancer (BC) risk factors and mammographic density (MD) patterns is not clear, high MD is well known as an independent risk factor for BC. Thus, the aim of this study was to examine the association between MD and BC risk factors in BC patients and find a correlation between MD and tumor characteristics in BC patients. Methods: Our data included 242 patients with BC. Furthermore, the MD (type I - <25%; type II - 25–50%; type III - 51–75%; and type IV - >75%) was categorized according to percentile density, and the various types of MD were compared using risk factors for BC and tumor characteristics of patients. Results: The results of this study indicated that younger age, pre-menopausal status, younger menarche age, nulliparity, low body mass index, and smoking significantly increase the percentage of MD (p<0.001, p<0.001, p=0.04, p<0.001, p=0.003, and p=0.01, respectively). Moreover, the distribution of MD patterns showed significant differences according to tumor subtypes. Type 4 mammographic pattern was higher in patients with human epidermal growth factor receptor 2 (Her2) type of tumor (p=0.01). Conclusion: Higher MD is related to reproductive risk factors and tumor subtypes, especially Her2 type, in BC patients. Further studies are needed to identify the factors related to breast density.
Objective: Although the relationship between breast cancer (MK) risk factors and mammographic dancite (MD) pattern is not clear, it is known that high MD is an independent risk factor for MK. The aim of this study is to explore the relationship between MD and MK risk factors and tumor characteristics in MK patients. Tools and methods: The study included 242 MK patients. MD was categorized according to the dancite percentages (type I-<25%; type II-25%-50%; type III-51%-75%; type IV->75%) and the risk factors used for breast cancer and tumor characteristics of patients were compared between these groups belonging to MD. The findings: The study found a significant relationship between increased MD percent in breast cancer patients and youth, premenopausal condition, prematurity age, unbornness, low body mass index and smoking (p<0.001, p<0.001, p=0.04, p<0.001, p=0.003, p=0.01, respectively). Additionally, the distribution of MD percent is also significantly different according to the tumor subtypes. In type 4 mammographic dancitis, the frequency of tumors of each type 2 is significantly high (p=0.01). The result: High MD is associated with reproductive risk factors in breast cancer patients and especially her2 type tumor. In breast cancer patients, more comprehensive studies are needed to identify the factors associated with MD. (SETB 2020-12-249)
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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