Özet:

This study examined the luteolithic effect and the resulting pregnancy rate by applying PGF2α in low doses from different ways. After synchronization (15 mg Luprostiol IM) randomly divided into 3 groups, without any disorders in the tubular genital organs and showing ovarian activity in the age of 2-3 years, Luprostiol 15 mg intramuscular, which is an analogy of a prostaglandin F2a in the 1st group (IM), injected in the 2nd group (IVSM) 3.75 mg intravulva-submukozal and in the 3rd group (IO) 0.75 mg intraovarian. The amount of plasma progesterone was determined by gathering blood samples for 5 days before and after the injection. According to the observation of external symptoms of asthma and assessment by determining the plasma progesterone amount, one of the three groups of animals did not develop luteolysis. Luteolysis was observed in all the remaining animals (4 animals) of the IM and IO prostaglandin-applicated group (80%) and luteolysis was observed in 2 of the 4 animals (40%) of the IVSM prostaglandin-applicated group (40%) while luteolysis was observed in the remaining 2 (40%) of the luteolysis. The plasma progesterone levels fell below 1 ng/ml in animals in the 1st and 3rd groups in 24 hours after the drug was administered, while the 2nd group remained at a higher level than those in Nazareth. Based on the external signs of estrogen, in the IM and IVSM groups of estrogen 49-72. In contrast to the observation that it was concentrated between the hours, the IO group formed in a period earlier than the other two groups (24-36 hours). According to the signs of asthma in the second half of this period, the rate of pregnancy in animals applied to sun seed was the highest in the IO group (% 100).