Objectives: Salivary gland neoplasms are less than 5% of all head and neck neoplasms (1). Although there are morphological similarities between different neoplasms, there may be catchy morphological differences in a single tumour. According to the World Health Organization (WHO), 4th Head and Neck Tumours Classification oncocytic salivary gland lesions are classified as nodular oncocytic hyperplasia, oncocytoma and oncocytic carcinoma. Oncocytic cells may be a component of other salivary gland neoplasms and metastatic malignities. Methods: In this study, salivary gland oncocytic lesions diagnosed in 2016-2017 were evaluated with Haematoxylin and Eosin (H&E) sections and PAS, diastase resistance PAS, p63, DOG1, cytokeratin7 (CK7), androgen receptor (AR) and PAX8 stains. Results: Nineteen cases were benign, two cases were malignant. Eighteen of the benign lesions were Warthin tumour (WT), one case was oncocytoma with nodular oncocytic hyperplasia. Acinic cell carcinoma (AciCCA) with oncocytic cells predominant was one of the malignant cases. The other case was high-grade salivary duct carcinoma (SDCA). Conclusion: The rarity and heterogeneity of this group of lesions may cause difficulties in diagnosis. We present histochemical and immunohistochemical findings of these lesions in light of the literature.
Purpose: Tuberculosis (TBT) constitutes less than 5% of all head neck tumors. There are distinct morphological similarities between the tumor types, as well as a remarkable morphological diversity within the same tumor. These tumors 4. According to the World Health Organization (WHO), oncocytic lesions are grouped as nodular oncocytic hyperplasia, oncocytoma and oncocytic carcinoma. Oncocytic cells take the mind of metastatic malignities as they may be a component of many primary spine gland neoplasms. The purpose of the distinctive diagnosis was to share our experiences in this group where many injury were placed. GereN and YINTEM: Oncocytic lesions of the sperm gland diagnosed in our clinic in the years 2016-2017 4. In light of the classification of DSO headache tumors, hematoxylene eosine cuts have been re-evaluated with periodic acid shift (PAS), diastasis-resistant periodic acid shift (D-PAS) and p63, DOG1, sitoceratine 7 (CK7), androgen receptor (AR), PAX8, CD10 immune-histochemical determinants. 19 of 21 have been benign, and 2 have been malign. 18 of the benign injury are Warthin tumor (WT), while 1 occurrence is considered oncositom accompanied by nodular oncostic hyperplasia and is notable because it is a rare case. One of the incidents that were diagnosed malignant has been diagnosed asic cell carcinoma (AciCCA) from oncocytic cells, the other incidence has been diagnosed with high-degree sperm canal carcinoma (SDCA). The result: These groups of injury that we experience diagnosis difficulties due to rare observations in practice and morphological findings that may be heterogeneous are presented in the literature with histochemical and immune-histochemical findings.
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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