Özet:

We aimed to evaluate cardiac functions and electrocardiogram (ECG) parameters that are determinant in the development of atrial and ventricular arrhythmia in children with celiac disease.Twenty-eight patients with celiac disease followed up between March 2017 and June 2020 were evaluated retrospectively. 33 age-and sex-matched healthy children were included as the control group. Echocardiography (ECHO) and 12-lead ECG were performed in all patients and controls. Of the 28 patients, 16 were girls (57.1%) and their mean age was 9.46±4.20 years. The mean duration time of celiac disease was 2.17±2.21 years. The Tp-e interval, QTc, QTc dispersion, and Tp-e / QT ratio were detected longer in celiac patients than in the control group (p <0.05). The patients were divided into 2 groups as seronegative (patients adhering to the gluten free-diet (GFD)) and seropositive celiac patients (patients not adhering to the GFD). There was no statistically significant difference between the two groups in terms of age and gender. The Tp-e interval, Tp-e / QT and Tp-e / QTc was determined longer in seropositive celiac patients. We found prolonged Tp-e interval, QTc, QTc dispersion and Tp-e / QT ratio in patients with celiac disease. In other words, we only detected the ventricular arrhythmia indicators as longer. In addition, we found prolonged Tp-e interval, Tp-e / QT and Tp-e / QTc in patients not adhering to a strict GFD. We detected that untreated celiac patients have a higher risk of ventricular arrhythmia. We think that further studies with more pediatric celiac patients who have longer duration of disease are needed for precise interpretation.

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