Abstract:

Eosinophilic colitis (EC), which is rare but has adverse effects on the quality of life, is an important reason for chronic diarrhea. However there is limited publishing related to EC in our country and here we aim to share our clinic's data on this issue. Material and Method: The subjects, who had colonoscopy and were diagnosed with EC with reference to pathological examination, were included in the study to analyze the chronic diarrhea aetiology between May 2016 and June 2020. Demographic qualifications, clinical features, laboratory results, colonoscopy and pathological data of the patients have been studied in as retrospectively. Results: Total 36 subjects including 22 men and 14 women, were involved in the study. The average age of men was 42. 6 (23 to 67 years) and the age average of women was 52.2 (18 to 75 years). The main clinical application reasons were diarrhea, stomach ache and rectal bleeding. The complaint period before diagnosis is 13.7 months (2 to 48) and the follow-up period after diagnosis is 16.5 months (2 to 49). The peripheral eosinophilia was detected with 7 out of 36 cases. Methylprednisolone was administered by patients as 16 to 32 mg/day as a dose. Discussion and Conclusion: The EC is an important cause of chronic diarrhea that affects the quality of life. Methylprednisolone treatment is extremely efficient and safe. The clinical suspicion and examination of colonoscopy biopsy are important factors for diagnosis.

Keywords: