Abstract:

Purpose: In our study, we intended to retrospective the factors affecting our biochemical nuts rate in localized prostate cancer after radical prostatectomy. Instruments and Methods: Factors affecting the biochemical node in 84 patients who were applied open retropubic radical prostatectomy due to prostate cancer localized in our clinic between March 2009 and February 2019 were evaluated as retrospective. Patients' preoperative PSA values, D'Amico risk classification according to risk groups, body mass index, age, postoperative Gleason score, and biochemical nickes were recorded. The biochemical niche was considered to be 0.2 ng/ml and above in two consecutive measurements and to show an increase in PSA. It has been studied whether these factors are associated with biochemical nuts. Results: In a total of 17 patients (20.2 percent) were detected biochemical nuts, while 67 (79.8 percent) were not detected. There was no statistically significant difference between the biochemical nickness rates in localized prostate cancer patients, which were divided into two groups of low risk and average high risk (p = 0.251). The preoperative PSA and postoperative Gleason scores were found statistically significantly different between the two groups (p =0.034 and p =0.023 respectively). The result: Preoperative PSA and postoperative Gleason scores are factors affecting the biochemical nickel. Patient tracking according to D'Amico risk groups should be carried out taking into account the guidelines, but it should not be neglected that tracking should be personalized if necessary.

Keywords: