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25
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4
Back ground: Cystoscopic examination and histological evaluation of bladder tissues are considered the gold standard for initial diagnosis of bladder cancer. For decades, researchers explore novel, non-invasive, specific and sensitive biomarkers for preliminary diagnosis and surveillance of bladder carcinoma. Exosomes are nano-sized vesicles present in various biological fluids and encapsulate huge number of biomarkers such as proteins, mRNAs and miRNAs. Caveolin-1(Cav-1) is a major protein of caveolae structure that expressed in a variety of cells and has a fundamental regulatory role in cancer development. Therefore, determination ofexosomal Cav-1 expression in different stages of bladder cancer is a critical concern for clinical diagnosis and prognosis.
Alan : Sosyal, Beşeri ve İdari Bilimler
Dergi Türü : Uluslararası
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