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Çocuk Olguda Nadir Bir İleus Nedeni: Sitomegalovirüs Koliti
2019
Journal:  
Türkiye Çocuk Hastalıkları Dergisi
Author:  
Abstract:

 Sitomegalovirüs (CMV) birincil veya edinsel immün yetmezliği olan kişilerde farklı organ sistemlerinin tutulumu ile ciddi klinik tablolara yol açabilir. CMV koliti karın ağrısı, diare, hematokezya, melena veya ateş gibi klinik semptomlar ile kendini gösterebilir. CMV kolitine bağlı striktür nadir bir komplikasyondur. Bu olgu sunumunda ileus nedeni ile konsülte edilen, immün yetmezlikli bir hastadaki CMV kolitine bağlı ileum ve kolon striktürü paylaşılmıştır.  Bare Lenfosit Sendromu ile birlikte kombine immün yetmezlik tanısı nedeni ile takip edilen 2 yaşındaki erkek hasta, bir aydır süren ishal ve pnömoni nedeniyle pediatri yoğun bakım yatırıldı. Tetkiklerinde CMV PCR pozitif olması üzerine tedaviye gansiklovir eklendi. Gaitada gizli kan olması üzerine pediatrik gastroenteroloji tarafından kolonoskopi yapıldı. Alınan biyopsi sonucu CMV koliti olarak geldi. Takipte ileus gelişen hastanın kolon grafisinde çıkan kolon segmentinin dar olduğu ve kontrast maddenin terminal ileuma geçmediği görüldü. Laparatomi yapılan olguda terminal ileum ve çıkan kolonun striktüre olduğu görüldü. Striktüre bağırsak ansları rezeke edilerek ileokolik anastomoz yapıldı. Histomorfolojik bulgular CMV koliti olarak değerlendirildi. Hasta taburcu edilerek takibi için pediatriye yönlendirildi.  CMV, immün yetmezliği olan hastalarda gastrointestinal sistemde enfeksiyona yol açabilen fırsatçı bir virüstür. İmmün yetmezlikli çocuklarda ileus tablosuna yol açan nedenler arasında CMV koliti ve striktür ayırıcı tanıda düşünülmelidir. 

Keywords:

A Rare Cause of Ileus in Childhood: Cytomegalovirus Colitis
2019
Author:  
Abstract:

primary or acquired immune deficiency. CMV colitis may present with clinical symptoms such as abdominal pain, diarrhea, hematochezia, melena and fever. Stricture due to CMV colitis is a very rare complication. We discuss ileum and colon stricture due to CMV colitis in an immunodeficient patient in this paper.  The two-year-old male patient was being followed-up with combined immunodeficiency and the bare lymphocyte syndrome. He was hospitalized at the pediatric intensive care unit for diarrhea and pneumonia for the last month. CMV PCR was positive in the tests and Ganciclovir was therefore added to the treatment. Colonoscopy was performed for fecal occult blood by the pediatric gastroenterology unit. The biopsy result was as CMV colitis. The patient developed ileus during follow-up, and the colon graph with contrast revealed a narrow colon segment with the contrast agent unable to pass to the terminal ileum. Laparotomy was performed and strictures observed in the terminal ileum and the ascending colon. An ileocolic anastomosis was performed by resecting the bowel loops affected by stricture. The histomorphological findings were as CMV colitis. The patient was discharged and referred for follow-up to the pediatric service.  Cytomegalovirus is an opportunistic virus that can lead to the infection of the gastrointestinal system in individuals with immunodeficiency. CMV colitis and stricture should be considered in the differential diagnosis in immunodeficient children with ileus symptoms.

Keywords:

A Rare Cause Of Ileus In A Child Case: Cytomegalovirus Colitis
2019
Author:  
Abstract:

 with primary or acquired immune deficiency. CMV colitis may present with clinic symptoms such as abdominal pain, diarrhea, hematochezia, melena and fever. Stricture due to CMV colitis is a very rare complication. We discuss ileum and colon stricture due to CMV colitis in an immunodeficient patient in this paper.  The two-year-old male patient was being followed-up with combined immunodeficiency and the bare lymphocyte syndrome. He was hospitalized at the pediatric intensive care unit for diarrhea and pneumonia for the last month. CMV PCR was positive in the tests and ganciclovir was therefore added to the treatment. Colonoscopy was performed for fecal occult blood by the pediatric gastroenterology unit. The biopsy result was reported as CMV colitis.  The patient developed ileus during follow-up, and the colon graph with contrast revealed a narrow colon segment with the contrast agent unable to pass to the terminal ileum. Laparotomy was performed and strictures observed in the terminal ileum and the ascending colon. An ileocolic anastomosis was performed by resecting the bowel loops affected by stricture. The histomorphologic findings were reported as CMV colitis. The patient was discharged and referred for follow-up to the pediatric service.  Cytomegalovirus is an opportunistic virus that can lead to the infection of the gastrointestinal system in individuals with immunodeficiency. CMV colitis and stricture should be considered in the differential diagnosis in immunodeficient children with ileus symptoms. 

Keywords:

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Türkiye Çocuk Hastalıkları Dergisi

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

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Article : 1.066
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Türkiye Çocuk Hastalıkları Dergisi