This study aimed to evaluate the effects of the ivermectin used in the treatment of bovine papillomatosis on serum TNF-α and IL-6. Nine cattle with different ages (15-20 months old), breed (4 male Brown Swiss, 3 female Brown Swiss, 1 female Native Black, 1 female Holstein with clinically bovine papillomatosis were included. After taking blood samples from all animals, ivermectin at a dose of 0.2 mg/kg was administered subcutaneously as a single dose. On the 7, 22 and 52nd days after the first application, blood sampling and the monitoring of the animals were repeated. Four animals (1 Brown Swiss and 3 Brown Swiss) and two animals (2 Brown Swiss) regressed nearly 90-100 % and 70-80 %, respectively while in other animals (1 Native Black and 2 Brown Swiss) no remission was observed during the observation period. Serum TNF-α and IL-6 levels were determined to have increased on the 7th day and decreased on the 22nd and 52nd days following the administration, but no statistically significance (p>0.05). It was concluded that ivermectin might be effective on clinically recovery and serum TNF-α and IL-6 levels. More comprehensive future studies on higher numbers of animals are warranted.
This study aimed at evaluating the effects of the ivermectin used in the treatment of bovine papillomatosis on serum TNF-α and IL-6. Nine cattle with different ages (15-20 months old), breed (4 male Brown Swiss, 3 female Brown Swiss, 1 female Native Black, 1 female Holstein with clinically bovine papillomatosis were included. After taking blood samples from all animals, ivermectin at a dose of 0.2 mg/kg was administered subcutaneously as a single dose. On the 7, 22 and 52nd days after the first application, blood sampling and the monitoring of the animals were repeated. Four animals (1 Brown Swiss and 3 Brown Swiss) and two animals (2 Brown Swiss) regressed
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
Benzer Makaleler | Yazar | # |
---|
Makale | Yazar | # |
---|