The purpose of this study is to search the most important factors that determine the capital structure of the firms in the industrial and service sectors of Istanbul Stock Exchange (ISE) by using CRT (Classification and Regression Trees) algorithm of data mining techniques. For this purpose 38 indicators are chosen from different financial fields such as profitability, liquidity, activity efficiency, market value, firm size, business risk, none-debt tax shield, tax level and growth rates. Empirical results of the study show that the most important factors affect capital structures of firms are liquidity, activity efficiency and business risk
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