It is known that interest is the most important factor which effect students‟ achievements and attainment of knowledge. The aim of this study is to explore the high school students‟ interest towards to usage of organic chemistry in daily life. The data for this survey study was collected through a questionnaire containing 27 Likert- type items ranging from 1 (low) to 4 (high). The items were formed by taking the use of organic chemistry in daily life into consideration to determine the levels of stu- dents‟ interest. Participants were 505 ninth, tenth and eleventh grade students, 229 of them were girls and 276 of them were boys. According to results, students have the highest interest in “the mummification techniques used in preserving corpses in Egypt”. However the lowest interest rates were shown in “what antifreeze is? and how it acts?”. Although the highest interest was found in science major students, there was no statistically significant difference between these students and the other students. The results of the present study can be used in the development of curricu- lum and/or in the design of the text content.
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