In this study, seven members of the OECD in East-Central European countries were examined the comparative performance of biotechnological development. For this purpose, data envelopment analysis method was used. 1998 and 2011 data were selected for comparative analysis. According to “CCR Model” and “Super Efficiency Model”, Slovakia and Slovenia has spurted for 13 years. In all other countries, there is a loss of performance. In terms of seven countries’ performance, Turkey’s is quietly remarkable. Turkey was in an advantageous position compared to all other countries in 1998. But It lagged behind Slovakia and Slovenia in 2011. This situation demonstrates that Turkey needs to reconsider the national innovation system
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