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Objectives: Gastric cancer is the fifth most common cancer and the third most common cause of cancer-related deaths in the world. In this study, we aimed to evaluate the impact of clinicopathological factors on overall survival in the patients who underwent curative-intent gastrectomy due to gastric adenocarcinoma. Methods: The medical records of 644 patients who underwent gastrectomy between January 2007 and January 2017 in our clinic were retrospectively reviewed. Among these patients, 359 patients were included in this study. The impact of several prognostic factors on survival was investigated. Results: The mean age was 59.2±11.6 (29-83). Male/female ratio was 2.12. The median follow-up time was 19 months (CI=10.1-31.1). Median overall survival was 23±2.3 months (CI=18.3-27.6). Splenectomy, R1 (microscopically incomplete) resection, and advanced stage were independent risk factors for poor prognosis. Conclusion: R1 resection, splenectomy, and advanced TNM stage were associated with poor prognosis in gastric cancer. Splenectomy should be avoided in the absence of direct invasion of the tumour or metastasis of lymph nodes on splenic hilum to prevent postoperative infectious complication-related mortality.
Mast cancer is the fifth most common cancer in the world and the third most common cause of cancer-related deaths. In this study, we aimed at evaluating the overall effect of clinical pathological factors on survival in patients with curative gastrectomy depending on stomach adenocarcinoma. Method: The medical records of 644 patients with gastrectomy in our clinic between January 2007 and January 2017 were retrospective. 359 of these patients were included in the study. The effects of various prognostic factors have been studied. Results: The average age was 59.2 ± 11.6 (29-83) The male/female ratio was 2.12. The media follow-up period was 19 months (CI = 10.1-31.1). The average overall survival was 23 ± 2.3 months (CI = 18.3-27.6). Splenectomy was found as independent risk factors for R1 (microscopic incomplete) recession and advanced stage tumor poor prognosis. The result: in stomach cancer, R1 resection, splenectomy and advanced TNM stages were found associated with poor prognosis. In the event of tumor invasion or no lymphatic nod metastasis, splenectomy should be avoided due to the risk of mortality due to postoperative infectious complications. (SETB-2020-09-183)
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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