Özet:

Colorectal cancer (CRC) is the third most common malignancy worldwide. According to Pakistan Annual Cancer Registry Report, it is the second most common cancer an males and sixth most common cancer amongst females.There are multiple histopathological factors which have an impact on prognosis and survival in CRC.Colorectal cancer (CRC) is the third most common malignancy worldwide. According to Pakistan Annual Cancer Registry Report, it is the second most common cancer an males and sixth most common cancer amongst females.There are multiple histopathological factors which have an impact on prognosis and survival in CRC.The features of prognostic significance include perineural invasion, lymphovascular invasion, infiltrating tumor borders, poorly defined clusters, Extra mural venous invasion (EMVI) and tumor budding.The main purpose of our study is to calculate tumor budding according to the method proposed by ITBCC in pT2 colorectal carcinomas and study its association with other prognostic indicators

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