Özet:

INTRODUCTION AND OBJECTIVE: In addition to the methods of imaging in the diagnosis and prognosis of cerebrovascular disease (SVH), the clinical importance of new biochemical indicators added every day is increasing. Our study aims to identify the relationship between soluble-CD40 ligand (sCD40L), average thrombocytes (MPV) and average erythrosite volume (MCV) levels in ischemic and hemorrhagic SVHs with early prognosis and mortality METHODS and RESPONSIBILITY: The study included 100 ischemic and 80 hemorrhagic injury patients and 230 individuals consisting of 50 healthy volunteer control groups. The demographic data of each patient and the Glasgow Koma scales, the ISC score and the NIHSS scores, the blood MPV, MCV, sCD40L levels were recorded in patients with intraserebral bleeding. There is no significant difference between patient groups and control group in terms of sCD40L and MCV levels. The MPV levels were observed significantly higher in patients with ischemic and hemorrhagic stroke compared to the control group. 22.2% of the patients who suffered a stroke lost their lives within the first week. The sCD40L values were observed significantly lower in the dead patients compared to the sCD40L values in the living patients. There is no significant difference between living and dead patients in terms of MCV and MPV levels. PROTECTION and RESULTS: MPV levels increase significantly in patients who apply to acute stroke. Low serum sCD40L levels at the moment of the first diagnosis may indicate that early prognosis will be worse in patients with acute stroke.

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