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AKUT GASTROENTERİTLE ÇOCUK POLİKLİNİĞİNE BAŞVURAN HASTALARDAKİ ROTAVİRÜS VE ENTERİK ADENOVİRÜS SIKLIĞI Frequency of Rotavirus and Enteric Adenovirus Infection in Children with Acute Gastroenteritis Admitted to Children Outpatient Clinic
2020
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ÖZET Amaç: Çocuklarda akut gastroenterit yüksek mortalite ve morbidite ile seyredebilmektedir. Akut gastroenterit tanı ve tedavi yaklaşımlarında viral etkenler çoğunlukla göz ardı edilerek endikasyon dışı ampirik antibiyotik kullanılması çok sık rastlanılan bir durumdur. Bu çalışmada çocuk polikliniğine akut gastroenterit nedeniyle başvuran hastalardaki rotavirüs ve adenovirüs sıklığının belirlenmesi amaçlanmıştır. Gereç ve Yöntemler: Ocak 2018-Ocak 2019 tarihleri arasında hastanemize ishal nedeniyle başvuran 518 hasta retrospektif olarak incelendi. Dışkı örneklerinde rotavirus ve adenovirus antijenlerinin varlığı immünokromatografik yöntemle ROTA/ADENO (Acrobiotech, USA) kiti ile üretici firma önerileri doğrultusunda kalitatif olarak değerlendirildi. Bulgular: Çalışmaya 518 ishalli olgu alındı. 49 olguda (% 9.4) rotavirüs antijen pozitif, 5 vakada (% 0.96) adenovirüs pozitif idi. Mevsimlere göre değerlendirildiğinde; rotavirüs % 18 lik bir oran ilesık kış ayında görüldü, adenovirüs ise % 2.5 ilesık sonbaharda rastlandı. Yaşlara göre bakıldığında ise rotavirüs ve adenovirüssık 6-10 yaş arasında saptandı. Sonuç: Akut gastroenteritlerin tanı ve tedavisinde özellikle kış aylarında rotavirüs ve adenovirüs etken olarak düşünülmelidir. Rotavirüs oranının literatürden daha düşük çıkması aşılanma bilincinin artmasına bağlanabilir. Rutin aşı takvimine girerse bu oranın daha da azalacağını düşünüyoruz. Anahtar Kelimeler: Adenovirüs; Akut Gastroenterit; Rota virüs ABSTRACT Objective: Acute gastroenteritis in children may progress with high mortality and morbidity. It is a common practice using antibiotics for treatment of diarrhea in children usually without taking into account viral agents. In this study, we aimed to investigate the frequency of rotavirus and adenovirus antigen positivity in children with acute gastroenteritis admitted to children outpatient clinic. Material and Methods: A total of 518 children who applied between January 2018 and January 2019, with complaints of acute gastroenteritis, were investigated retrospectively. Presence of rotavirus and adenovirus antigens in stool samples was evaluated qualitatively with the immunochromatographic method, ROTA / ADENO (Acrobiotech, USA) kit according to the manufacturer's recommendations. Results: Five-hundred-eighteen diarrhea cases were included in the study. Rotavirus antigen was positive in 49 cases (9.4 %), adenovirus was positive in 5 cases (0.96 %). When evaluated according to the seasons; rotavirus was most common in winter, at a rate of 18 %, adenovirus, on the other hand, was most common in the fall with 2.5 %. According to the ages, rotavirus and adenovirus were most common between the ages of 6-10. Conclusion: In the diagnosis and treatment of acute gastroenteritis especially in winter, rotavirus and adenovirus should be considered as agents. The fact that the rotavirus rate is lower than the literature may be related to increased awareness of vaccination. We think that this rate will decrease even more if the routine enters the vaccination schedule. Keywords: Acute Gastroenteritis; Adenovirus; Rotavirus

Anahtar Kelimeler:

AKUT GASTROENTERİTLE ÇOCUK POLİKLİNİĞİNE BAŞVURAN HASTALARDAKİ ROTAVİRÜS VE ENTERİK ADENOVİRÜS SIKLIĞI Frequency of Rotavirus and Enteric Adenovirus Infection in Children with Acute Gastroenteritis Admitted to Children Outpatient Clinic
2020
Yazar:  
Özet:

Acute gastroenteritis in children can be seen with high mortality and morbidity. In acute gastroenteritis diagnosis and treatment approaches, viral factors are often ignored and the use of unindicated ampyric antibiotics is a very common condition. This study aims to determine the frequency of rotavirus and adenovirus in patients who apply to a child clinic due to acute gastroenteritis. Tools and Methods: From January 2018 to January 2019, 518 patients who were applied to our hospital due to diarrhea were examined retrospectively. The presence of rotavirus and adenovirus antigen in the extract samples was qualitatively assessed in accordance with the manufacturer’s recommendations by the immunochromatographic method with the ROTA/ADENO (Acrobiotech, USA) kit. The study contains 518 cases of infection. In 49 cases (9.4%) rotavirus antigen was positive, in 5 cases (0.96) adenovirus was positive. When assessed by seasons, rotavirus was seen at a rate of 18% in the winter, while adenovirus was found at a rate of 2.5% in the autumn. Rotavirus and adenovirus were identified between the ages of 6-10 years. In the diagnosis and treatment of acute gastroenteritis, it should be considered as a factor of rotavirus and adenovirus, especially in winter months. The lower rate of rotavirus than literature can be linked to an increase in vaccination consciousness. If we get into the routine vaccine calendar, we think this rate will be even lower. Keywords: Adenovirus; Acute Gastroenteritis; Rota virus ABSTRACT Objective: Acute gastroenteritis in children may progress with high mortality and morbidity. It is a common practice using antibiotics for the treatment of diarrhea in children usually without taking into account viral agents. In this study, we aimed to investigate the frequency of rotavirus and adenovirus antigen positivity in children with acute gastroenteritis admitted to children outpatient clinic. Material and Methods: A total of 518 children who applied between January 2018 and January 2019, with complaints of acute gastroenteritis, were investigated retrospectively. The presence of rotavirus and adenovirus antigen in stool samples was evaluated qualitatively with the immunochromatographic method, ROTA / ADENO (Acrobiotech, USA) kit according to the manufacturer's recommendations. Results: Five-hundred-eighteen cases of diarrhea were included in the study. Rotavirus antigen was positive in 49 cases (9.4 %), adenovirus was positive in 5 cases (0.96 %). When evaluated according to the seasons; rotavirus was most common in winter, at a rate of 18%, adenovirus, on the other hand, was most common in the fall with 2.5%. According to the ages, rotavirus and adenovirus were most common between the ages of 6-10. In the diagnosis and treatment of acute gastroenteritis especially in winter, rotavirus and adenovirus should be considered as agents. The fact that the rotavirus rate is lower than the literature may be related to increased awareness of vaccination. We think that this rate will decrease even more if the routine enters the vaccination schedule. Keywords: Acute Gastroenteritis; Adenovirus; Rotavirus

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